2A5B Polyclonal Antibody, 20ul Antibody Humanization The Ku p70/p86 dimer acts

The Ku p70/p86 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold

Recruits and targets histone methyltransferases SUV420H1 and SUV420H2| leading to epigenetic transcriptional repression

Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma

TARPs regulate both trafficking and channel gating of the AMPA receptors

2A5B Polyclonal Antibody, 20ul Antibody Humanization The Ku p70/p86 dimer actsThe product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser Thr phosphatases and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme which is composed of a catalytic subunit and a constant regulatory subunit that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate