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Human Acid Sphingomyelinase-like Phosphodiesterase 3B, SMPDL3B ELISA Kit , 96T Bottle-Top Dispenser reduces the recruitment of inhibitor-of-apoptosis

SKU: 28165764209

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Human Acid Sphingomyelinase-like Phosphodiesterase 3B, SMPDL3B ELISA Kit , 96T Bottle-Top Dispenser reduces the recruitment of inhibitor-of-apoptosisLipid modulating phosphodiesterase (PubMed: 26095358). Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll like receptor signaling (By similarity). Has in vitro phosphodiesterase activity, but the physiological substrate is unknown (PubMed: 26095358). Lacks activity with phosphocholine containing lipids, but can cleave CDP choline, and

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Description

reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2

subunit:Interacts with EPS15

enteropathy

Binding of the SH2 domains of PI3K to phosphotyrosines on IRS1 leads to the activation of PI3K and the generation of phosphatidylinositol-(3

Human Acid Sphingomyelinase-like Phosphodiesterase 3B, SMPDL3B ELISA Kit , 96T Bottle-Top Dispenser reduces the recruitment of inhibitor-of-apoptosisLipid modulating phosphodiesterase (PubMed: 26095358). Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll like receptor signaling (By similarity). Has in vitro phosphodiesterase activity, but the physiological substrate is unknown (PubMed: 26095358). Lacks activity with phosphocholine containing lipids, but can cleave CDP choline, and

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