Bay 60-7550 - CAS# 439083-90-6 Size:Solid 10 mg AZD1981 exhibited good cross-species binding

AZD1981 exhibited good cross-species binding activity against mouse

5-dimethoxyphenyl]quinoline-3-carboxamide bis(methanesulfonic acid) trihydrate

Formula: C47H80O17

DAF-FM DA is a reagent to detect and quantify low concentrations of nitric oxide (NO)

Bay 60-7550 - CAS# 439083-90-6 Size:Solid 10 mg AZD1981 exhibited good cross-species bindingBAY 60 7550 is a potent PDE2 inhibitor with IC50 values of 2. 0 nM (bovine) and 4. 7 nM (human). BAY 60 7550 antagonizes oxidative stress induced anxiety like behavioral effects in mice by increasing cGMP signaling. Phosphodiesterases (PDEs) are key regulatory enzymes of intracellular cAMP cGMP levels. These second messengers play important regulatory roles in controlling steroidogenesis in the adrenal. Disruption of PDEs has been associated with a