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Fludarabine phosphate - CAS# 75607-67-9 Catalog No.:M10602-10 4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl phosphonato)oxy]methyl}-3
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Fludarabine phosphate - CAS# 75607-67-9 Catalog No.:M10602-10 4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl phosphonato)oxy]methyl}-3Fludarabine phosphate is t he phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara A) with antineoplastic activity. Fludarabine phosphate is rapidly dephosphorylated to 2 fluoro ara A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2 fluoro ara ATP. This metabolite may inhibit DNA polymerase alpha, ribonucleotide reductase and DNA primase, thereby
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