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INCB024360 analogue(IDO-IN-1) - CAS# 914471-09-3 size:2mg solid PubMed PMID: 24845199

INCB024360 analogue(IDO-IN-1) - CAS# 914471-09-3 size:2mg solid PubMed PMID: 24845199

Name: INCB024360 analogue(IDO-IN-1) - CAS# 914471-09-3 size:2mg solid PubMed PMID: 24845199
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INCB024360 analogue(IDO-IN-1) - CAS# 914471-09-3 size:2mg solid PubMed PMID: 24845199INCB14943, also known as INCB024360 analog, IDO5L and IDO IN 2 with CAS#914471 09 3, CAS No. 914471 09 3, is a potent and orally available hydroxyamidine and inhibitor of indoleamine 2, 3 dioxygenase (IDO1) with potential immunomodulating and antineoplastic activities. INCB024360 analog is a potent (HeLa IC50=19 nM) competitive inhibitor of IDO. Testing of INCB024360 analog in mice demonstrated pharmacodynamic inhibition of IDO, as measured by

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Description

PubMed PMID: 24845199

Smiles: CCCCCNC(=O)N1CC(CN(CC2C=CC(Cl)=CC=2)CC2=CC=C(S2)[N+]([O-])=O)CC1

Chemical Name: 4-(4-(5

PubMed PMID: 30655275

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