GSK2141795 Catalog No.:M8725-10 A Safety Study of LY2886721

A Safety Study of LY2886721 Multiple Doses is performing in Healthy Subjects

(2011) Cancer Res

The proliferative responses of allogeneic CD4(+) T cells to Suplatast tosilate-treated DCs are suppressed

Gyrd-Hansen M

GSK2141795 Catalog No.:M8725-10 A Safety Study of LY2886721Uprosertib, also known as GSK2141795 and GSK795, is an orally bioavailable inhibitor of the serine threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K Akt signaling pathway is frequently