Nesolicaftor K5182 blocks LPS-induced NF-kB activation

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Nesolicaftor K5182 blocks LPS-induced NF-kB activationNesolicaftor (PTI 428) is a specific cystic fibrosis transmembrane conductance regulator (CFTR) amplifier that increases CFTR expression. Product information CAS Number: 1953130 87 4 Molecular Weight: 354. 36 Formula: C18H18N4O4 Synonym: PTI 428 PTI 428 PTI428 Chemical Name: N (trans 3 [5 [(1R) 1 hydroxyethyl] 1,3,4 oxadiazol 2 yl]cyclobutyl) 3 phenyl 1,2 oxazole 5 carboxamide Smiles: C[C@@H](O)C1=NN=C(O1)[C@@H]1C[C@H](C1)NC(=O)C1=CC(=NO1)C1C=CC=CC=1

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