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SB 239063 - CAS# 193551-21-2 zone Maleate InChiKey: LOLHUPGCPDURJG-UHFFFAOYSA-N

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SB 239063 - CAS# 193551-21-2 zone Maleate InChiKey: LOLHUPGCPDURJG-UHFFFAOYSA-NSB239063 is a potent p38MAPK inhibitor. SB 239063 had an IC(50) of 44 nM for inhibition of recombinant purified human p38alpha. In lipopolysaccharide stimulated human peripheral blood monocytes, SB 239063 inhibited interleukin 1 and tumor necrosis factor alpha production (IC(50) values = 0. 12 and 0. 35 microM, respectively). SB 239063 may be useful for the treatment of asthma and other inflammatory disorders. Product information CAS Number: 193551 21

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Description

InChiKey: LOLHUPGCPDURJG-UHFFFAOYSA-N

Formula: C28H22F3N7O

selective and ATP-competitive mTOR inhibitor (IC50 = 2

4-dihydro-5-((5-nitro-2-thiazolyl)thio)-3H-1

SB 239063 - CAS# 193551-21-2 zone Maleate InChiKey: LOLHUPGCPDURJG-UHFFFAOYSA-NSB239063 is a potent p38MAPK inhibitor. SB 239063 had an IC(50) of 44 nM for inhibition of recombinant purified human p38alpha. In lipopolysaccharide stimulated human peripheral blood monocytes, SB 239063 inhibited interleukin 1 and tumor necrosis factor alpha production (IC(50) values = 0. 12 and 0. 35 microM, respectively). SB 239063 may be useful for the treatment of asthma and other inflammatory disorders. Product information CAS Number: 193551 21

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