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AZ 628 643 Smiles: O=C(OCC1C=C(Cl)C=C(Cl)C=1)N1CCN(CCC(=O)C2=CC3OC(=O)NC=3C=C2)CC1

AZ 628 643 Smiles: O=C(OCC1C=C(Cl)C=C(Cl)C=1)N1CCN(CCC(=O)C2=CC3OC(=O)NC=3C=C2)CC1

Name: AZ 628 643 Smiles: O=C(OCC1C=C(Cl)C=C(Cl)C=1)N1CCN(CCC(=O)C2=CC3OC(=O)NC=3C=C2)CC1
Brand: www.drbramiyohan.com
SKU: 84334163291
Price: 90.00 USD
Availability: InStock
Rating: 4.18 (13 reviews)

SKU: 84334163291

4.2

SEK90.00 SEK113.00

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AZ 628 643 Smiles: O=C(OCC1C=C(Cl)C=C(Cl)C=1)N1CCN(CCC(=O)C2=CC3OC(=O)NC=3C=C2)CC1AZ 628 is a selective, orally available Raf inhibitor with excellent pharmacokinetic properties and robust tumor growth inhibition in xenograft studies ( (IC50 values are 29, 34 and 105 nM for c Raf1, B RafV600E and wild type B Raf, respectively). AZ 628 inhibits growth, and induces cell cycle arrest and apoptosis in colon and melanoma cell lines with the B RafV600E mutation. Product information CAS Number: 878739 06 1 Molecular Weight: 451. 52

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Description

Smiles: O=C(OCC1C=C(Cl)C=C(Cl)C=1)N1CCN(CCC(=O)C2=CC3OC(=O)NC=3C=C2)CC1

) treatment also loweres blood glucose in the ob/ob mice by 40%

InChiKey: DECBQELQORZLLP-UAIOPKHMSA-N

Hara-Nishimura I

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