Obatoclax (GX15-070) Catalog No.:M7923-10 Cardiogenol C either solves in

Cardiogenol C either solves in water or DMSO generates a similar effect

resulting in reduced levels of nuclear β-catenin

Formula: C44H53ClN10O8S

c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun

Obatoclax (GX15-070) Catalog No.:M7923-10 Cardiogenol C either solves inObatoclax, also known as GX 015 070, a synthetic small molecule inhibitor of the bcl 2 family of proteins with potential pro apoptotic and antineoplastic activities. Obatoclax binds to members of the Bcl 2 protein family, preventing the binding of these anti apoptotic proteins to the pro apoptotic proteins Bax and Bak and so promoting the activation of the apoptotic pathway in Bcl 2 overexpressing cells. The Bcl 2 family of proteins (bcl 2, bcl xl,