Netupitant metabolite Monohydroxy Netupitant ilin ) displays dose-dependent antitumor activity

) displays dose-dependent antitumor activity

resulting in its trafficking through HDAC6 to perinuclear aggresomes without cytokine stimulation or SOCS-1 induction

10-diazatetracyclo[12

PAI-039 exerts antithrombotic efficacy in rat models of arterial and venous vascular injury without effecting platelet aggregation

Netupitant metabolite Monohydroxy Netupitant ilin ) displays dose-dependent antitumor activityMonohydroxy Netupitant is the metabolite of Netupitant which is a potent and selective neurokinin 1 receptor (NK1) receptor antagonist. It is achiral and orally active. Product information CAS Number: 910808 12 7 Molecular Weight: 594. 59 Formula: C30H32F6N4O2 Synonym: Monohydroxy Netupitant Chemical Name: 2 [3,5 bis(trifluoromethyl)phenyl] N {4 [2 (hydroxymethyl)phenyl] 6 (4 methylpiperazin 1 yl)pyridin 3 yl} N,2 dimethylpropanamide Smiles: