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(R)-(+)-Etomoxir Sodium Salt Size:Solid 2 mg It comprises a ligand for

SKU: 76343948545

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PLN120.00 PLN159.00

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(R)-(+)-Etomoxir Sodium Salt Size:Solid 2 mg It comprises a ligand forEtomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1 (CPT 1) on the outer face of the inner mitochondrial membrane. This prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria. This step is essential to the production of ATP from fatty acid oxidation. Etomoxir has also been identified as a direct agonist of PPAR.

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Description

It comprises a ligand for Von Hippel Lindau (VHL) protein joined by a linker to a cereblon targeting ligand

Chemical Name: 1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3

[Epub ahead of print] PubMed PMID: 27352067

BRN0123183

(R)-(+)-Etomoxir Sodium Salt Size:Solid 2 mg It comprises a ligand forEtomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1 (CPT 1) on the outer face of the inner mitochondrial membrane. This prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria. This step is essential to the production of ATP from fatty acid oxidation. Etomoxir has also been identified as a direct agonist of PPAR.

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