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A769662 - AMPK Activator. CAS# 844499-71-4 size:10mg solid Chemical Name: N-[(3

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A769662 - AMPK Activator. CAS# 844499-71-4 size:10mg solid Chemical Name: N-[(3A769662, CAS No. 844499 71 4, is a potent and selective small molecule activator of AMP activated protein kinase (AMPK). It induces allosteric activation of AMPK and inhibition of dephosphorylation of AMPK on Thr 172, similar to the effects of AMP. The activation of AMPK inhibits mTOR signaling, which is a positive effector of cell growth and survival. A769662 stimulated partially purified rat liver AMPK with an EC50 of 0. 8 M and inhibited fatty acid

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Chemical Name: N-[(3

Brain Penetrant LRRK2 Inhibitorn (2012) ACS Med

Epub 2009 Oct 6

c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun

A769662 - AMPK Activator. CAS# 844499-71-4 size:10mg solid Chemical Name: N-[(3A769662, CAS No. 844499 71 4, is a potent and selective small molecule activator of AMP activated protein kinase (AMPK). It induces allosteric activation of AMPK and inhibition of dephosphorylation of AMPK on Thr 172, similar to the effects of AMP. The activation of AMPK inhibits mTOR signaling, which is a positive effector of cell growth and survival. A769662 stimulated partially purified rat liver AMPK with an EC50 of 0. 8 M and inhibited fatty acid

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