Signal · Product Feed

NMS-873 - ATPase VCP/p97 Inhibitor. CAS# 1418013-75-8 0321 InChi: InChI=1S/C27H29NO3/c1-5-31-26(30)23-17(2)28-21-15-27(3

NMS-873 - ATPase VCP/p97 Inhibitor. CAS# 1418013-75-8 0321 InChi: InChI=1S/C27H29NO3/c1-5-31-26(30)23-17(2)28-21-15-27(3

Name: NMS-873 - ATPase VCP/p97 Inhibitor. CAS# 1418013-75-8 0321 InChi: InChI=1S/C27H29NO3/c1-5-31-26(30)23-17(2)28-21-15-27(3
Brand: www.drbramiyohan.com
SKU: 66178317470
Price: 60.00 USD
Availability: InStock
Rating: 4.378 (10 reviews)

SKU: 66178317470

4.4

USD60.00 USD86.00

Pay in 4 interest-free payments of $15.00 Learn more

Shipping Estimate
USA

USA

CAN

Ships within 48 hours · Estimated delivery Aug 25 - Aug 30

Live Spec

NMS-873 - ATPase VCP/p97 Inhibitor. CAS# 1418013-75-8 0321 InChi: InChI=1S/C27H29NO3/c1-5-31-26(30)23-17(2)28-21-15-27(3NMS 873, CAS NO. 1418013 75 8, is a potent and specific small molecule allosteric inhibitor of the ATPase VCP p97 (IC50 ~0. 03 M), identified by a high throughput screening. It is very selective (IC50 >10 M) against all of the AAA ATPases, HSP90 or the 53 kinases tested. Using photo affinity labeling, structural analysis and mutagenesis, the binding site of NMS 873 was found to be a region spanning the D1 and D2 domains of adjacent protomers

Store: www.drbramiyohan.com · Domain: www.drbramiyohan.com

Description

InChi: InChI=1S/C27H29NO3/c1-5-31-26(30)23-17(2)28-21-15-27(3

Solubility: Soluble in DMSO

Solubility: DMSO: ≥ 45 mg/mL

Smiles: CC(C)(C(=O)N[C@H]1C2=CC=CC=C2C2=CC=CC=C2NC1=O)C(=O)NCC(F)(F)C(F)(F)F

Exchange/Return Notes