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GSK591 (EPZ015866) - PRMT5 Inhibitor. CAS# 1616391-87-7 Catalog No.:M60321-10S InChi: InChI=1S/C35H49F2N7O4/c1-5-34(6-2

GSK591 (EPZ015866) - PRMT5 Inhibitor. CAS# 1616391-87-7 Catalog No.:M60321-10S InChi: InChI=1S/C35H49F2N7O4/c1-5-34(6-2

Name: GSK591 (EPZ015866) - PRMT5 Inhibitor. CAS# 1616391-87-7 Catalog No.:M60321-10S InChi: InChI=1S/C35H49F2N7O4/c1-5-34(6-2
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GSK591 (EPZ015866) - PRMT5 Inhibitor. CAS# 1616391-87-7 Catalog No.:M60321-10S InChi: InChI=1S/C35H49F2N7O4/c1-5-34(6-2GSK591, also known as EPZ015866 and GSK3203591, CAS No. 1616391 87 7, is a chemical probe for PRMT5. In an in vitro biochemical assay, GSK591 potently inhibits the PRMT5 MEP50 complex from methylating (histone) H4 with IC50 = 11 nM. In Z 138 cells, GSK591 inhibits the symmetric arginine methylation of SmD3 with EC50 = 56 nM. Further, GSK591 is selective for PRMT5 (up to 50 micromolar) relative to a panel of methyltransferases. Product information CAS

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InChi: InChI=1S/C35H49F2N7O4/c1-5-34(6-2

InChi: InChI=1S/C18H13F3N4O2/c19-18(20

InChi: InChI=1S/C28H40BrN7O4/c1-16(2)35(12-6-11-31-27(39)34-18-9-7-17(8-10-18)28(3

CX-4945 (Silmitasertib)

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