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Afuresertib - CAS# 1047644-62-1 Catalog No.:M6803-10 -20oC 1 year

Afuresertib - CAS# 1047644-62-1 Catalog No.:M6803-10 -20oC 1 year

Name: Afuresertib - CAS# 1047644-62-1 Catalog No.:M6803-10 -20oC 1 year
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Afuresertib - CAS# 1047644-62-1 Catalog No.:M6803-10 -20oC 1 yearAfuresertib, CAS No. 1047644 62 1, also known as GSK 2110183 or GSK 2110183C, is an orally bioavailable inhibitor of the serine threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Afuresertib binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K Akt signaling pathway is

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Description

-20oC 1 year

43 μM) and causes altered cell cycle progression most clearly revealed under conditions of recovery from serum starvation

is a potent inhibitor of ferroptosis with an EC50 ~60 nM

FT-0644594

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