MK-4827 - CAS# 1038915-60-4 92 (benzenesulfonate) PubMed PMID: 24664237
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MK-4827 - CAS# 1038915-60-4 92 (benzenesulfonate) PubMed PMID: 24664237Niraparib, also known as MK4827, is an orally active, potent and selective poly(ADP Ribose) polymerase (PARP) inhibitor that radiosensitizes human lung and breast cancer cells. Niraparib inhibits PARP1 PARP2 with IC50 of 3. 8 nM 2. 1 nM respectively. Niraparib is currently in Phase 3 clinical trials for ovarian cancer and BRCA+ breast cancer. Product information CAS Number: 1038915 60 4 Molecular Weight: 320. 39 Formula: C19H20N4O Synonym: Niraparib
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