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E-7050 Size:Solid 10 mg In vitro release and permeation

SKU: 54650585577

4.6
SEK90.00 SEK117.00

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E-7050 Size:Solid 10 mg In vitro release and permeationGolvatinib, also known as E7050, is an orally bioavailable dual kinase inhibitor of c Met (hepatocyte growth factor receptor) and VEGFR 2 (vascular endothelial growth factor receptor 2) tyrosine kinases with potential antineoplastic activity. c Met VEGFR kinase inhibitor E7050 binds to and inhibits the activities of both c Met and VEGFR 2, which may inhibit tumor cell growth and survival of tumor cells that overexpress these receptor tyrosine kinases.

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Description

In vitro release and permeation studies revealed that the different amounts of ethanol used influenced the release profiles of etofenamate

and GSK3β

2011 May 11

Molecular Weight: 628

E-7050 Size:Solid 10 mg In vitro release and permeationGolvatinib, also known as E7050, is an orally bioavailable dual kinase inhibitor of c Met (hepatocyte growth factor receptor) and VEGFR 2 (vascular endothelial growth factor receptor 2) tyrosine kinases with potential antineoplastic activity. c Met VEGFR kinase inhibitor E7050 binds to and inhibits the activities of both c Met and VEGFR 2, which may inhibit tumor cell growth and survival of tumor cells that overexpress these receptor tyrosine kinases.

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