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ORY-1001 (RG-6016) - LSD1 Inhibitor. CAS# 1431326-61-2 60252 Remodelin was used at 1-10

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ORY-1001 (RG-6016) - LSD1 Inhibitor. CAS# 1431326-61-2 60252 Remodelin was used at 1-10ORY 1001, CAS No. 1431326 61 2, is a highly potent and selective inhibitor of Lysine Specific Demethylase 1 (LSD1) with IC50 <20 nM. It is highly selective over related enzymes such as MAO A B. ORY 1001 affects AML stem cells, a sub population of cancer cells that has been proposed to be responsible for frequent relapses of the disease. It significantly reduces tumor cell load and increases survival time in mouse models of Acute Lymphoblastic

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Description

Remodelin was used at 1-10 µM in vitro and cellular assays

Molecular Weight: 302

2008 Nov 1

CUDC-907 induces apoptosis and G2–M cell-cycle arrest in cancer cells and effectively inhibits more than 50 different cancer cells’ growth

ORY-1001 (RG-6016) - LSD1 Inhibitor. CAS# 1431326-61-2 60252 Remodelin was used at 1-10ORY 1001, CAS No. 1431326 61 2, is a highly potent and selective inhibitor of Lysine Specific Demethylase 1 (LSD1) with IC50 <20 nM. It is highly selective over related enzymes such as MAO A B. ORY 1001 affects AML stem cells, a sub population of cancer cells that has been proposed to be responsible for frequent relapses of the disease. It significantly reduces tumor cell load and increases survival time in mouse models of Acute Lymphoblastic

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