Tasisulam(LY573636) - CAS# 519055-62-0 060 a potent Wee1 inhibitor
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Tasisulam(LY573636) - CAS# 519055-62-0 060 a potent Wee1 inhibitorTasisulam, also known as LY573636, CAS No. 519055 62 0, is an acyl sulfonamide with potential antineoplastic activity. Selectively toxic towards tumor cells, tasisulam appears to induce tumor cell apoptosis by a mitochondrial targeted mechanism involving the loss of mitochondrial membrane potential and induction of reactive oxygen species (ROS). In combination with an angiogenesis inhibitor, this agent may exhibit synergistic antiangiogenic activity.
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