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Eltrombopag (Olamine) ntherin A Smiles: C[C@H]1O[C@@H]2[C@@H](CO1)O[C@@H](O[C@H]1[C@H]3COC(=O)[C@@H]3[C@@H](C3=CC4OCOC=4C=C31)C1=CC(OC)=C(O)C(=C1)OC)[C@H](O)[C@H]2O

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Eltrombopag (Olamine) ntherin A Smiles: C[C@H]1O[C@@H]2[C@@H](CO1)O[C@@H](O[C@H]1[C@H]3COC(=O)[C@@H]3[C@@H](C3=CC4OCOC=4C=C31)C1=CC(OC)=C(O)C(=C1)OC)[C@H](O)[C@H]2OEltrombopag is a small molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production. Eltrombopag was

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Description

Smiles: C[C@H]1O[C@@H]2[C@@H](CO1)O[C@@H](O[C@H]1[C@H]3COC(=O)[C@@H]3[C@@H](C3=CC4OCOC=4C=C31)C1=CC(OC)=C(O)C(=C1)OC)[C@H](O)[C@H]2O

CAS Number: 1355324-14-9

PubMed PMID: 25966657

InChi: InChI=1S/C15H18O2/c1-8-4-7-12-10(3)15(16)17-14(12)13-9(2)5-6-11(8)13/h5

Eltrombopag (Olamine) ntherin A Smiles: C[C@H]1O[C@@H]2[C@@H](CO1)O[C@@H](O[C@H]1[C@H]3COC(=O)[C@@H]3[C@@H](C3=CC4OCOC=4C=C31)C1=CC(OC)=C(O)C(=C1)OC)[C@H](O)[C@H]2OEltrombopag is a small molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production. Eltrombopag was

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