TAK-779 Catalog No.:M10030-2 PubMed PMID: 26721364

PubMed PMID: 26721364

Hoechst 33342 is a DNA minor groove binder used fluorochrome for visualizing cellular DNA

9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide

Amifostine is a phosphorothioate proposed as a radiation-protective agent

TAK-779 Catalog No.:M10030-2 PubMed PMID: 26721364TAK 779 is a C C chemokine receptor type 5 (CCR5) receptor antagonist potentially for the treatment of HIV infection. Treatment with TAK 779 reduced incidence and severity of experimental autoimmune encephalomyelitis. It strongly inhibited migration of CXCR3 CCR5 bearing CD4+, CD8+ and CD11b+ leukocytes to the CNS. TAK 779 did not reduce proliferation of anti myelin oligodendrocyte glycoprotein T cells, the production of IFN gamma by T cells or CXCR3