PRI-724 - CAS# 1422253-38-0 317 DASA-58 (40 μM) treated cells

DASA-58 (40 μM) treated cells are injected into male SCID-bg/bg mice bearing PC3 tumors by IV

CK-1827452 does not affect the phosphorylation status of myofilament proteins in both WT and KO hearts as shown by the absence of significant differences between pre and post CK-1827452 samples within WT and KO groups

is a potent JNK inhibitor

21(22):7107-17

PRI-724 - CAS# 1422253-38-0 317 DASA-58 (40 μM) treated cellsPRI 724, CAS No. 1422253 38 0, also known as C 82 prodrug ICG 001 analog, is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity. Wnt signaling pathway inhibitor PRI 724 specifically inhibits the recruiting of beta catenin with its coactivator CBP (the binding protein of the cAMP response element binding protein CREB); together with other transcription factors beta catenin CBP