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Gemcitabine (elaidate) KII-IN-1 Formula: C19H19N5O

SKU: 37317740351

4.4
PLN100.00 PLN120.00

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Gemcitabine (elaidate) KII-IN-1 Formula: C19H19N5OGemcitabine elaidate, also known as CO 101 and CP 4126, is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di and tri phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide

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Description

Formula: C19H19N5O

CK-1827452 does not affect the phosphorylation status of myofilament proteins in both WT and KO hearts as shown by the absence of significant differences between pre and post CK-1827452 samples within WT and KO groups

PF-03716556 is highly selective for H+

In a similar study on rabbits

Gemcitabine (elaidate) KII-IN-1 Formula: C19H19N5OGemcitabine elaidate, also known as CO 101 and CP 4126, is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di and tri phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide

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