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Bisindolylmaleimide I (GF109203X) - CAS# 133052-90-1 size:2mg solid 1093/jxb/erx483

Bisindolylmaleimide I (GF109203X) - CAS# 133052-90-1 size:2mg solid 1093/jxb/erx483

Name: Bisindolylmaleimide I (GF109203X) - CAS# 133052-90-1 size:2mg solid 1093/jxb/erx483
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SKU: 35291045773
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SKU: 35291045773

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Bisindolylmaleimide I (GF109203X) - CAS# 133052-90-1 size:2mg solid 1093/jxb/erx483Bisindolylmaleimide I (GF109203X), a potent and highly selective PCK inhibitor., CAS No. 133052 90 1, is a potent and highly selective PCK inhibitor. bisindolylmaleimide I(GF 109203X )inhibits PKC isozymes alpha, beta 1, beta 2, gamma, delta and epsilon in vitro . GF 109203X inhibited GSK 3 in vitro, when assayed either in cell lysates (IC(50) 360 nM or in GSK 3beta immunoprecipitates (IC(50) 170 nM derived from rat epididymal adipocytes. Pretreatment

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Description

1093/jxb/erx483

223645-67-8 (free base)

a direct substrate of JNK kinase

InChi: InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H

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