Ezatiostat Catalog No.:M10357-2 5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino}phenol

5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino}phenol

Chemical Name: ethyl 2-[[(2S)-2-[(7-chloro-2-oxo-1H-quinolin-6-yl)sulfonylamino]-2-(2-methoxyphenyl)acetyl]-(thiophen-2-ylmethyl)amino]acetate

CAS Number: 459789-99-2

and the Kd for recombinant UCHL5 is higher (14-18 μM) compared to that of USP14

Ezatiostat Catalog No.:M10357-2 5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino}phenolEzatiostat is a liposomal small molecule glutathione analog inhibitor of glutathione S transferase (GST) P1 1 with hematopoiesis stimulating activity. After intracellular de esterification, the active form of ezatiostat binds to and inhibits GST P1 1, thereby restoring Jun kinase and MAPK pathway activities and promoting MAPK mediated cellular proliferation and differentiation pathways. This agent promotes the proliferation and maturation of