CX-6258 (hydrochloride hydrate) Size:Solid 10 mg CCT251545 (70mg/kg

CCT251545 (70mg/kg

ERK) is evident by the response to Derazantinib treatment

InChi: InChI=1S/C30H26F2N4O5/c1-5-40-28-16-36(23-8-6-18(31)12-17(23)2)35-29(28)30(37)34-19-7-9-25(21(32)13-19)41-24-10-11-33-22-15-27(39-4)26(38-3)14-20(22)24/h6-16H

In the presence of 10 μM TBB (and 100 μM ATP) only CK2 is drastically inhibited (>85%) whereas three kinases (phosphorylase kinase

CX-6258 (hydrochloride hydrate) Size:Solid 10 mg CCT251545 (70mg/kgCX 6258 is a pan Pim kinases inhibitor with excellent biochemical potency and kinase selectivity. CX 6258 exhibited in vitro synergy with chemotherapeutics and robust in vivo efficacy in two Pim kinases driven tumor models. Inhibition of Pim kinases is expected to have a beneficial effect as cancer therapy. Product information CAS Number: 1353858 99 7 Molecular Weight: 516. 42 Formula: C26H27Cl2N3O4 Chemical Name: (3E) 5 chloro 3 ({5 [3 (4 methyl 1,4