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PFI-4 - BRPF1 Bromodomain Inhibitor. CAS# 900305-37-5 0020 an IkappaB ubiquitination inhibitor

PFI-4 - BRPF1 Bromodomain Inhibitor. CAS# 900305-37-5 0020 an IkappaB ubiquitination inhibitor

Name: PFI-4 - BRPF1 Bromodomain Inhibitor. CAS# 900305-37-5 0020 an IkappaB ubiquitination inhibitor
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SKU: 24191751807
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SKU: 24191751807

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PFI-4 - BRPF1 Bromodomain Inhibitor. CAS# 900305-37-5 0020 an IkappaB ubiquitination inhibitorPFI 4, CAS No. 900305 37 5, is a potent, selective and cell permeable BRPF1 bromodomain inhibitor. It binds to BRPF1B with a Kd of 13 nM (ITC). It has general >100 fold selectivity against other bromodomains including BRPF2, BRPF3 and BRD4. It reduces recovery time in triple BRD cell construct in FRAP and is potent in cells with IC50 250 nM, while showing no effect on BRPF1A. Product information CAS Number: 900305 37 5 Molecular Weight: 380. 44

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Description

an IkappaB ubiquitination inhibitor

Solubility: DMSO: 77 mg/mL (185

but not to the extent of glucocorticoid inhibition

Molecular Weight: 521

Exchange/Return Notes