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MK-5108 Size:Solid 10 mg LY294002 provides a starting point

MK-5108 Size:Solid 10 mg LY294002 provides a starting point

Name: MK-5108 Size:Solid 10 mg LY294002 provides a starting point
Brand: www.drbramiyohan.com
SKU: 22433652753
Price: 113.05 USD
Availability: InStock
Rating: 4.7038 (13 reviews)

SKU: 22433652753

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PLN113.05 PLN156.05

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MK-5108 Size:Solid 10 mg LY294002 provides a starting pointMK 5108, also known as VX689, is a novel small molecule with potent inhibitory activity against Aurora A kinase. MK 5108 specifically inhibited Aurora A kinase in a panel of protein kinase assays. MK 5108 also induced phosphorylated Histone H3 in skin and xenograft tumor tissues in a nude rat xenograft model. MK 5108 inhibited growth of human tumor cell lines in culture and in different xenograft models. MK 5108 is currently tested in clinical trials

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Description

LY294002 provides a starting point for the generation of bromodomain inhibitors tapping the chemical space of kinase antagonists

PubMed PMID: 25420519

2016 Apr 19

2014 Feb 5

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