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Resminostat - CAS# 864814-88-0 Catalog No.:M10362-2 Lesley J Scott

Resminostat - CAS# 864814-88-0 Catalog No.:M10362-2 Lesley J Scott

Name: Resminostat - CAS# 864814-88-0 Catalog No.:M10362-2 Lesley J Scott
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Resminostat - CAS# 864814-88-0 Catalog No.:M10362-2 Lesley J ScottResminostat, also known as 4S 201 and RAS2410, is an orally bioavailable inhibitor of histone deacetylases (HDACs) with potential antineoplastic activity. Resminostat binds to and inhibits HDACs leading to an accumulation of highly acetylated histones. This may result in an induction of chromatin remodeling, inhibition of the transcription of tumor suppressor genes, inhibition of tumor cell division and the induction of tumor cell apoptosis. Product

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Description

Lesley J Scott

Formula: C10H14N4O4

Formula: C20H14ClNO2S

Co-crystal structures showed that PFI-1 acts as an acetyl-lysine (Kac) mimetic inhibitor efficiently occupying the Kac binding site in BRD2 and BRD4

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