XL147-II Size:2mg solid It brings about near complete

It brings about near complete degradation of TBK1 in mutant K-Ras and wild-type cancer cell lines with no significant effect of proliferation

and serves as an excellent chemical probe for investigating DOT1L and further development of DOT1L inhibitors for cancer therapy

or causing hypoglycemia

reduces muscle membrane damage

XL147-II Size:2mg solid It brings about near completeXL147 II is an ATP competitive inhibitor of class I PI3K isoforms. It acts by abrogating Akt and S6 phosphorylation in HER2+ cells and also inducing the expression and phosphorylation of HER3 and other RTKs. Product information CAS Number: 956958 53 5 Molecular Weight: 448. 52 Formula: C21H16N6O2S2 Synonym: XL147 derivative II Chemical Name: N [3 (2, 1, 3 Benzothiadiazol 5 ylamino) 2 quinoxalinyl] 4 methyl benzenesulfonamide Smiles: