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Sal003 55283 PubMed PMID: 25296383

SKU: 15545483751

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SEK85.00 SEK135.00

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Sal003 55283 PubMed PMID: 25296383SAL 003 is a cell permeable inhibitor of eIF2 dephosphorylation. SAL003 is an Analog of salubrinal (Cat. No. 2347) with improved aqueous solubility. Sal003mediated upregulation of eIF2 phosphorylation suppressed cisplatininduced p53 activation. Furthermore, reduction of eIF2 phosphorylation by PERK knockdown enhanced cisplatin induced p53 activation and apoptosis. Product information CAS Number: 1164470 53 4 Molecular Weight: 463. 21 Formula:

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Description

PubMed PMID: 25296383

CAS Number: 361442-04-8

InChi: InChI=1S/C17H14O3/c18-15(11-9-13-5-1-3-7-16(13)19)12-10-14-6-2-4-8-17(14)20/h1-12

Bisindolylmaleimide

Sal003 55283 PubMed PMID: 25296383SAL 003 is a cell permeable inhibitor of eIF2 dephosphorylation. SAL003 is an Analog of salubrinal (Cat. No. 2347) with improved aqueous solubility. Sal003mediated upregulation of eIF2 phosphorylation suppressed cisplatininduced p53 activation. Furthermore, reduction of eIF2 phosphorylation by PERK knockdown enhanced cisplatin induced p53 activation and apoptosis. Product information CAS Number: 1164470 53 4 Molecular Weight: 463. 21 Formula:

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