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BX-912 535ye 993 5-3(6)1-2-4(7)8/h1-16

SKU: 11807334278

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USD90.00 USD134.00

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BX-912 535ye 993 5-3(6)1-2-4(7)8/h1-16BX912 is a selective potent PDK1 inhibitor with IC50 of 12 nM. BX912 blocks PDK1 Akt signaling in tumor cells and suppresses the anchorage dependent growth of a variety of tumor cell lines (such as PC 3 cells) in culture or induces apoptosis. Product information CAS Number: 702674 56 4 Molecular Weight: 471. 35 Formula: C20H23BrN8O Chemical Name: N {3 [(5 bromo 4 {[2 (1H imidazol 5 yl)ethyl]amino}pyrimidin 2 yl)amino]phenyl}pyrrolidine 1 carboxamide

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Description

5-3(6)1-2-4(7)8/h1-16

by nucleic acid cross-linking followed by UV irradiation

3-dihydro-7H-[1

whereas the MTD of docetaxel combined with MS-209 greatly reduced MCF-7/ADM tumor growth

BX-912 535ye 993 5-3(6)1-2-4(7)8/h1-16BX912 is a selective potent PDK1 inhibitor with IC50 of 12 nM. BX912 blocks PDK1 Akt signaling in tumor cells and suppresses the anchorage dependent growth of a variety of tumor cell lines (such as PC 3 cells) in culture or induces apoptosis. Product information CAS Number: 702674 56 4 Molecular Weight: 471. 35 Formula: C20H23BrN8O Chemical Name: N {3 [(5 bromo 4 {[2 (1H imidazol 5 yl)ethyl]amino}pyrimidin 2 yl)amino]phenyl}pyrrolidine 1 carboxamide

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