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TGR5 Polyclonal Antibody, 100ul Centrifugal Filter It is expressed at low

SKU: 99819208787

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TGR5 Polyclonal Antibody, 100ul Centrifugal Filter It is expressed at lowGPBAR1 encodes a member of the G protein coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.

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Description

It is expressed at low levels in the cytoplasm of pro-B and pre-B cells and present on the cell surface only at mature stages of B-cell differentiation

Diseases associated with FAM3D include narcolepsy

The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking

is capable of binding specifically to methylated DNA

TGR5 Polyclonal Antibody, 100ul Centrifugal Filter It is expressed at lowGPBAR1 encodes a member of the G protein coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.

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