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PEX14 Polyclonal Antibody, 50ul Cell fragmentation and collection The encoded protein (ATR interacting

SKU: 99663068996

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PEX14 Polyclonal Antibody, 50ul Cell fragmentation and collection The encoded protein (ATR interactingThis gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.

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Description

The encoded protein (ATR interacting protein) binds to single-stranded DNA coated with replication protein A

It is a mainly cytoplasmic protein that can translocate to the cell membrane after cell stimulation

This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes

MIM 176948) (Nonami et al

PEX14 Polyclonal Antibody, 50ul Cell fragmentation and collection The encoded protein (ATR interactingThis gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.

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