Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma The 105 kD protein is

The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex

inducing leukocyte migration and activation

An important paralog of this gene is GK

Mitotic and Regulation of PLK1 Activity at G2/M Transition

Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma The 105 kD protein isMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.