I5P2 Rabbit Polyclonal Antibody, 20ul Lysosome has been associated with deletions

has been associated with deletions of chromosome 22q11

The secreted protein acidic and cysteine rich is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape

This enzyme produces wax esters by the esterification of long chain (or wax) alcohols with acyl-CoA-derived fatty acids

A pseudogene of this gene is located on the long arm of chromosome 7

I5P2 Rabbit Polyclonal Antibody, 20ul Lysosome has been associated with deletionsThis gene encodes a member of a family of inositol polyphosphate 5 phosphatases. These enzymes function in the regulation of calcium signaling by inactivating inositol phosphates. The encoded protein is localized to the cytosol and mitochondria and associates with membranes through an isoprenyl modification near the C terminus. Alternatively spliced transcript variants of this gene have been described.