SAE1 Polyclonal Antibody, 50ul ADME Cytokine receptor common subunit beta

Cytokine receptor common subunit beta encoded by CSF2RB is the common beta chain of the high affinity receptor for IL-3

Among its related pathways are Transport of glucose and other sugars

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter

Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia

SAE1 Polyclonal Antibody, 50ul ADME Cytokine receptor common subunit betaPosttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO activating enzyme for the sumoylation of proteins.