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HIF-1 alpha (Acetyl Lys532) Rabbit Polyclonal Antibody, 20ul Cell Dissociation oncogenic transformation and malignant cell

HIF-1 alpha (Acetyl Lys532) Rabbit Polyclonal Antibody, 20ul Cell Dissociation oncogenic transformation and malignant cell

Name: HIF-1 alpha (Acetyl Lys532) Rabbit Polyclonal Antibody, 20ul Cell Dissociation oncogenic transformation and malignant cell
Brand: www.drbramiyohan.com
SKU: 99239976624
Price: 111.00 USD
Availability: InStock
Rating: 4.0153 (19 reviews)

SKU: 99239976624

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HIF-1 alpha (Acetyl Lys532) Rabbit Polyclonal Antibody, 20ul Cell Dissociation oncogenic transformation and malignant cellContains two independent C terminal transactivation domains NTAD and CTAD which function synergistically. Their transcriptional activity is repressed by an intervening inhibitory domain (ID). Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions activates the transcription of over 40 genes including erythropoietin glucose transporters glycolytic enzymes vascular endothelial growth factor and

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Description

oncogenic transformation and malignant cell proliferation

Mutations in this gene result in pseudohypoaldosteronism type IIB

characterized by the lack of the A subunit alone

where the phosphorylated form is bound to a 14-3-3 protein

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