DOC11 Polyclonal Antibody, 50ul Cryogenic Vials It had previously been weakly

It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene

The gene of VN1R4 maps to chromosome 19q13

Expansion of a GGGGCC repeat from 2-22 copies to 700-1600 copies in the intronic sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778

This gene encodes a member of the non-histone lysine methyltransferases

DOC11 Polyclonal Antibody, 50ul Cryogenic Vials It had previously been weaklyThe DHR 2 domain is necessary for the GEF activity.,Guanine nucleotide exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the DOCK family.,Contains 1 DHR 1 (CZH 1) domain.,Contains 1 DHR 2 (CZH 2) domain.,Contains 1 PH domain.,subunit: Interacts with CDC42.,