c-Abl(Phospho-Tyr89) Rabbit Polyclonal Antibody, 50ul Hepatocytes intracellular N and C termini

intracellular N and C termini

is a 648 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain

The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration

The encoded protein maybe play a role in the ability of the replication fork to bypass DNA lesions

c-Abl(Phospho-Tyr89) Rabbit Polyclonal Antibody, 50ul Hepatocytes intracellular N and C terminiThis gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress. The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation suggesting a