AR Polyclonal Antibody, 100ul[BT-AP00566] Protein Post-translational Modification Two alternatively spliced transcript variants

Two alternatively spliced transcript variants encoding different isoforms are described for this gene

The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety

and regulation of cell shape

Containing six ANK repeats and thirty-seven exons

AR Polyclonal Antibody, 100ul[BT-AP00566] Protein Post-translational Modification Two alternatively spliced transcript variantsThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR