Phospho-ATR (S428) Polyclonal Antibody, 100ul Vessels Mutations in this gene have

Mutations in this gene have been associated with Oguchi disease

RhoB and RhoC are highly homologous

The phosphorylation of RAD17 checkpoint clamp loader component is required for the DNA-damage-induced cell cycle G2 arrest

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus

Phospho-ATR (S428) Polyclonal Antibody, 100ul Vessels Mutations in this gene haveThe protein encoded by ATR (ATR serine threonine kinase) belongs the PI3 PI4 kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1,