Glucocorticoid receptor Polyclonal Antibody, 100ul Bio-Reaction Tube Knockout studies in mice suggested

Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration

but upon binding of ligand is transported to the nucleus

Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546| 20937277)

It involves in translation termination in response to the termination codons UAA

Glucocorticoid receptor Polyclonal Antibody, 100ul Bio-Reaction Tube Knockout studies in mice suggestedNR3C1 encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. Nuclear receptor subfamily 3 group C member 1 is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses,