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SAP30 Polyclonal Antibody, 100ul Sampling Tubes The genetic defect leading to

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SAP30 Polyclonal Antibody, 100ul Sampling Tubes The genetic defect leading toHistone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A

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Description

The genetic defect leading to Huntington's disease may not necessarily eliminate transcription

An important paralog of this gene is HAP1

Contains 2 ANK repeats

as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle

SAP30 Polyclonal Antibody, 100ul Sampling Tubes The genetic defect leading toHistone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A

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