IL-17D Polyclonal Antibody, 100ul Diagnostic Probes & Oligos ABL1 has been found fused

ABL1 has been found fused to a variety of translocation partner genes in various leukemias

The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity

This gene has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family

Individual members of this family differ in the number of C-terminal TS motifs

IL-17D Polyclonal Antibody, 100ul Diagnostic Probes & Oligos ABL1 has been found fusedThe protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2 GM CSF. The increased expression of IL8 induced by this cytokine was found to be NF kappa B dependent.