M4K5 Polyclonal Antibody, 20ul Custom RNA Oligos Various mutations have been described

Various mutations have been described for this gene and have been linked to human diseases

It is expressed in the tissue and circulating myeloid leukocytes

The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins

|Functions as a master transcriptional regulator of the adaptive response to hypoxia

M4K5 Polyclonal Antibody, 20ul Custom RNA Oligos Various mutations have been describedThis gene encodes a member of the serine threonine protein kinase family, that is highly similar to yeast SPS1 STE20 kinase. Yeast SPS1 STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described