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Siah-1/2 Polyclonal Antibody, 20ul Low retention tips Anti-apoptotic protein which functions as

SKU: 96977460292

4.9
PLN111.00 PLN145.00

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Siah-1/2 Polyclonal Antibody, 20ul Low retention tips Anti-apoptotic protein which functions asSIAH1 encodes E3 ubiquitin protein ligase SIAH1 that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing

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Description

Anti-apoptotic protein which functions as a caspase-3 inhibitor

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The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity

These subunits are encoded by 6 different genes

Siah-1/2 Polyclonal Antibody, 20ul Low retention tips Anti-apoptotic protein which functions asSIAH1 encodes E3 ubiquitin protein ligase SIAH1 that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing

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