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Ku-70 Polyclonal Antibody, 100ul[BT-AP04894] Protein Post-translational Modification This gene is mapped to

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Ku-70 Polyclonal Antibody, 100ul[BT-AP04894] Protein Post-translational Modification This gene is mapped toThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

This gene is mapped to the chemokine receptor gene cluster region

which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins

The protein localizes to plasma membrane ruffles

Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres

Ku-70 Polyclonal Antibody, 100ul[BT-AP04894] Protein Post-translational Modification This gene is mapped toThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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