SIRT3 Polyclonal Antibody, 50ul Reservoirs This gene contains a variable

This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein

These subunits are encoded by families of related genes

Members of this family encode proteins containing a homeobox homology domain| proline rich region and Src-homology 3 (SH3) domain| and are components of the Abi/WAVE complex which regulates actin polymerization

and the counterbalancing phosphatase

SIRT3 Polyclonal Antibody, 50ul Reservoirs This gene contains a variableSIRT3 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular